Patented 100:1 plant sterol:sterolin ratio — a proprietary formulation competitors cannot replicate

Your immune system doesn't need a boost. It needs balance.

Moducare® supports a more intelligent approach to immune health — focused on balance rather than overstimulation. Instead of “boosting” the immune system, which can be counterproductive when it is already overactive or underactive, Moducare® helps support immune regulation using a clinically studied 100:1 ratio of plant sterols and sterolins.

These naturally occurring plant compounds help support the body’s ability to maintain healthy immune responses, whether that means calming excessive immune activity or supporting a weakened response. The result is a more balanced, adaptive immune system that can respond appropriately to everyday stressors, seasonal changes and environmental challenges.

Moducare supplement bottle with green cap on a leaf

The 100:1 Ratio — The Science Behind the Standard

The specific 100:1 ratio of beta-sitosterol to beta-sitosterolin is more than just a formulation choice — it is the ratio demonstrated in clinical research to produce the immune-modulating effects for which Moducare® is known.

Beta-sitosterolin, the companion compound, enhances the bioavailability and biological activity of the sterol — meaning that without the correct ratio, the immune-modulating effect is significantly diminished. This is the technical core of Moducare®'s clinical differentiation and the reason competitors cannot simply replicate the formula's efficacy without licensing the proprietary technology.

Supplement bottle labeled 'Moducare' with lemons and a lime on a neutral background

Bi-Directional Immune Regulation — The Clinical Advantage

Moducare®'s ability to support both a weakened immune system and calm an overactive one is its most clinically significant and commercially unique feature. This bi-directional regulation is achieved through the modulation of cytokine activity — influencing the balance between TH1 immune responses (associated with defence against infection) and TH2 responses (associated with allergic and inflammatory overreaction).

Clinical studies have investigated Moducare® across a range of conditions where this balance matters: from athletes experiencing training-induced immune suppression to individuals with chronic inflammatory and allergic conditions.

Nooxapellie NoddCare supplement bottle surrounded by green and purple plants

Cortisol Modulation — The Stress-Immunity Connection

One of Moducare®'s less commonly discussed but clinically supported benefits is its role in helping normalise cortisol levels. Cortisol — the body's primary stress hormone — has a well-established suppressive effect on immune function when chronically elevated. Plant sterols and sterolins have been shown to help moderate cortisol production, which means Moducare® addresses the stress-immunity connection at a physiological level. This makes it particularly relevant for athletes, professionals under sustained pressure and anyone experiencing the immune compromise that accompanies chronic stress.

The Science behind Moducare®

Breathe easy: Understanding allergic rhinitis and finding relief

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The Effect of Plant Sterols & Sterolins on Chronic Illness

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Exercise Induced Immune Suppression

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Scientifically proven to regulate your immune system.

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Moducare® Original — Plant Sterol Immune Modulator
Moducare® Original — Plant Sterol Immune Modulator

MOD001

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